World-Class, Innovative and Socially-Relevant
Established in January of 2020, the Ateneo Research Institute of Science and Engineering (ARISE) is a center for world-class, innovative and socially-relevant research initiatives of the School of Science and Engineering (SOSE). It enhances the research capacity and networking capability of SOSE to transform Philippine society through the generation of knowledge and innovative technologies for national development.
ARISE currently focuses on, but is not limited to, the following general research areas in line with the SOSE and University research agenda:
ARISE serves as the focal point for research programs, activities, and initiatives of SOSE.
Its establishment can be viewed as the Ateneo’s response to address important needs on several fronts.
At the national level, the country needs to develop, nurture and retain more researchers.
There is also a growing need for Research and Development units in both the private and public sectors. Unfortunately, it is costly to maintain such a unit, and it would be a lot more cost-effective if these will be pooled together, e.g., in a university setting.
Finally, there is a continuous push by the DOST and CHED to have inter-disciplinary research. ARISE is expected to align with these and fill in the need by DOST and CHED for such research partners.
Events & Announcements
Join us for the SOSE-ARISE Lecture Series for the School Year 2023-2024! Perspectives on Health and Wellness.
Topic: “Best Practices of Resilient Filipino Students”
Speaker: Dr. Queena N. Lee-Chua
Professor: Department of Mathematics
Time: 2:30 – 3:30 PM
Discover invaluable insights and gain a deeper understanding of resilience in Filipino students.
To register, simply click on the link below or scan the QR code on the poster:
Register Here- https://go.ateneo.edu/SOSEARISELectureSeries
Don’t miss out on this enlightening session! Spread the word and invite your friends to join us. Let’s come together for a healthier, happier, and more resilient future!
What does it mean for climate research to be people-centered? For research to be a form of care?
What are best practices and approaches on incorporating the knowledge, experience, and values of “users”, “stakeholders”, and indigenous communities in producing and assessing climate research?
What can Ateneo contribute to the paradigm of doing “research as care” in developing a bottom-up approach to regional (SEA) and local climate risk?
Join the My Climate Risk – Ateneo de Manila University Regional Hub in discussing these questions and more at the MCR Brown Bag Session: “Research as Care.” Gain and share insights on “research as care” and how this aligns with the first two Laudato Si’ goals: Response to the Cry of the Earth, and Response to the Cry of the Poor.
23 May, Tuesday, 3:00 – 5:00PM
Faber Hall 302
Limited slots available! Register at https://bit.ly/AIS23May
Learn more about other activities for Laudato Si’ week: https://www.ateneo.edu/…/ais-laudato-si-week-celebration
My Climate Risk (MCR) is a lighthouse activity of the World Climate Research Programme (WCRP). This event is organized in partnership with the Ateneo Research Institute of Science and Engineering (ARISE)
Attention all aspiring Atenean scientists and engineers! Are you interested in gaining hands-on experience in microfluidics fabrication, biotech instrumentation, science communication, diagnostics hardware, or material synthesis? Look no further than the Unsilo Labs Internship Program!
Join us for our information session on April 14, 2023, 5-6PM at CTC 413 to learn more about this exciting opportunity. Pre-register at: https://forms.gle/uWsUnazNuSZJPySJ9
This internship program is open to all year levels and any degree program.
We’re happy to share with you our 2021-2022 ARISE Annual Report.
Congratulations and thank you to the men and women of SOSE for the excellent work despite the challenges of the time. We also thank our internal and external partners for their generous assistance and support.
Here is the link for the SOSE ARISE Lecture Series
Zoom Registration: https://go.ateneo.edu/SOSEARISELectureSeries
Thank you very much.
We look forward to seeing you online
Paving the way for a pandemic-resilient Philippines!
Research teams from ARISE visited the DOST-MIRDC TSSS and AMCen facilities last July 20, 2022 as part of an ongoing effort to improve access to medical diagnostics through continuing research and local manufacturing.
With their expertise in precision metalwork, medium-to-large-scale plastics production, and additive manufacturing, these facilities present an opportunity for the technologies developed at ARISE to move from the research prototype stage towards widely-deployable biomedical equipment.
In particular, the miPCR Project, a portable molecular diagnostic platform for COVID-19 response funded by DOST-PCHRD and developed at ARISE, is a prime candidate for this transition. The miPCR Project recently concluded its Phase-I technical validation and is moving towards optimization and production scale-up.
Engineering solutions to be developed through the IPRDC Program* were also a key point of discussion during the visit and further highlighted the opportunities for engagement with the DOST-MIRDC TSS and AMCen facilities in the future.
*The ARISE project teams present at this event are under the Integrated Protein R&D Center (IPRDC) engineering wing led by Dr. Ricardo Guerrero and Ms. Danielle Lapinig.
Funded by the DOST-S4CP NICER Program and led by Dr. Crisanto Lopez, the IPRDC was initiated in early 2022 with the aim of establishing local production of key biologics for research and medical use through its four component projects covering biochemistry, production scale-up, instrumentation, and materials development.
IPRDC was conceived in response to shortages of key biological components used in lab-based diagnostic tests (e.g. enzymes, antibodies, etc.) during the COVID-19 pandemic, and is envisioned to play a significant role in supporting local biomedical industries in the future (e.g. vaccine production, medical research).
Graduating Biology Seniors Win Big at National Systematic Biologists Forum
Graduating students of the Ateneo Biodiversity Research Laboratory of the Department of Biology
received the top two awards for undergraduate oral presentations at the Young Systematic
Biologists Forum (YSBF). The forum was held at the 39 th Scientific and Annual Meeting of the
Association of Systematic Biologists of the Philippines (ASBP) last May 31 to June 2, 2022.
Enrico Gerard S. Sanchez (BS Bio ’22) won First Prize for his presentation entitled “Tiny, mighty, and
many: Five new species of Anacaena Thomson, 1859 (Coleoptera, Hydrophilidae) discovered from
high-altitude areas in the Philippines using integrative taxonomy”. His thesis adviser is Dr. Emmanuel
Delocado and his co-adviser is Prof. Hendrik Freitag. Previously, Gero also won the Dean’s Choice
Award in the Student Research Symposium held during the School of Science and Engineering (SOSE)
In his presentation, Gero talked about the five new species of Anacaena water scavenger beetles he
discovered and erected by coupling morphological and molecular approaches. He highlighted the
necessity to discover species from underexplored localities given the lack of comprehensive
knowledge on the freshwater diversity in the Philippines and the rapid insect extinction happening
globally. Being conducted amidst the pandemic lockdowns, the study is noteworthy as it involved
devising an innovative lab-at-home set-up and virtual walkthroughs, as well as on-site lab work when
restrictions were much lighter. When asked about the status of his publication by the panel, Gero
shared that the first paper from his undergraduate thesis was accepted for publication and is under
production in a Scopus-indexed journal.
Meanwhile, Christalle Beatriz N. Seno and Maureen Lianne T. Pascual (BS Bio ’22) secured Second
Prize for their presentation entitled “Species Survey of Ancyronyx Erichson, 1847 (Coleoptera:
Elmidae) in Greater Mindanao”. The thesis adviser of the study is Prof. Freitag and the co-adviser is
In their presentation, Bea and Mau shared about the new species of Ancyronyx spider riffle beetle
they described from the provinces of Samar, Siargao, Cotabato, Bukidnon, and Basilan. Specimens
utilized in their study were collected years prior from numerous expeditions of the Ateneo
Biodiversity Research Laboratory. The duo studied morphological, molecular, and ecological data to
support their identification of five new species of spider riffle beetle. Seno highlighted that the study
augments the current known diversity of the Ancyronyx in the Philippines, which was previously
limited to Mindoro, Palawan, and Negros.
Noting the quality of the students’ outputs, the judges of the YSBF inquired about the future plans of
the students. Gero shared that he will make sure to complete the writing and the publication
process of the other species in the next months. While he intends to pursue further studies at the
Ateneo School of Medicine and Public Health, he shared his genuine intention to visit the lab to help
train the junior students and to participate in future field expeditions. Bea, meanwhile, shared that
she will stay with the lab for a year as a research assistant. She will use the time to work on
publications and address some of the recommendations of the panelists.
Aside from the two studies mentioned, other members of the Ateneo Biodiversity Research
Laboratory presented orally as well. Jaymes Bryant S. Tibig (BS Bio ’22) delivered a talk entitled
“Integrative taxonomy of Dudgeodes Sartori, 2008 (Ephemeroptera: Teloganodidae) in the
Philippines, with description of three new species and supplementary egg descriptions” under the
mentorship of Dr. Jhoana Garces and Prof. Freitag.
Lastly, Dr. Delocado, Assistant Professor of the Department of Biology and Project Leader at the
Biodiversity Laboratory, shared the innovations being done by the lab to further biodiversity
knowledge amidst the pandemic restrictions. His talk entitled “Into the next possible: Stories and
insights on the changing landscape of biodiversity research and teaching of the Ateneo Biodiversity
Research Laboratory under the influence of the pandemic” is co-authored by Prof. Freitag and Dr.
Garces. The talk highlighted how the lab faculty and students employed creative problem solving
and collaboration to further research while following closely the restrictions imposed by the national
government and the health protocols of the university.
The studies presented by the students were made possible by the following grants: the SC Johnson
Environmental Leadership Development Fund for funding the innovative lab-at-home set-up, the
SOSE Industry 4.0 Research Fund (SI4) under the Ateneo Research Institute of Science and
Engineering (ARISE) for the previous field works and lab reagents and services, and the Biodiversity
Teaching in the Philippine-Cambodian-German Network (BIO-PHIL) for access to specimens.
BIOMOLECULAR R&D CAREER OPPORTUNITIES 2022-2026
in the BAYAN BIOMEDICAL LABORATORY at ATENEO DE MANILA UNIVERSITY
Dr Keith Moore PhD;
Dr Crisanto Lopez PhD & Dr Cybele Abad MD
A) The BAYAN Laboratory
B) The Programs
Three Programs are housed in the Ateneo Research Institute of Science & Engineering (ARISE).
1. Integrated Protein R&D Centre program (IPRDC, 2 projects) – 03/22 – 03/25.
2. Clinical development of a SARS-CoV2 genomic diagnostic (AMPLIFIED) – 09/22 – 03/24
3. Integrated Diagnostic Solutions program (IDS, 3 projects) – 01/23 – 01/26.
The programs are part of a common strategy that links all our applied life science R&D activities:
to catalyse the growth of molecular science teaching and research across all Philippine secondary schools and in all higher educational institutions
to design, develop & clinically evaluate affordable, accessible point of care diagnostics that are faster, cheaper and/or simpler than imported tests available to the majority of Filipinos.
to grow the Filipino biotechnology sector via the start-up formation of BAYAN Life Sciences.
C) The Projects
There are a total of eight ( projects in IPRDC, AMPLIFIED and IDS. Of these, six (6) are primarily based on microbiology, molecular biology, biochemistry, biophysics, and protein chemistry.
Integrated Protein R&D Centre (IPRDC):
1) “Enzyme Production: Cloning, Fermentation, Expression, Purification & Characterization”
2) “Scaling Up and Optimization of Bacterial Fermentation and Protein Expression”
3) “Clinical Development of a SARS-CoV2 Genomic Diagnostic Project (AMPLIFIED)”
Integrated Diagnostic Solutions (IDS):
4) “VANQUISHeD: Genomic & proteomic point of care diagnostics for viral diseases”.
5) “CAPTUReD: Genomic & proteomic point of care diagnostics for oncology”
6) “METABOLISeD: Genomic & proteomic point of care diagnostics for cardiometabolic diseases”.
D) Candidate profile
i. What we are looking for in candidates (scientific & technical skills)
We seek biology or chemistry graduates with a B.Sc, M.Sc, PhD and/or MD with a solid applied foundation in quantitative molecular sciences, assay development & expertise in recombinant protein production (IPRDC) or assay development & molecular diagnostics (IDS/AMPLIFIED). Experience of interdisciplinary research across biology, medicine, chemistry & engineering is an advantage.
The candidates must combine a strong theoretical foundation of molecular biology and biochemistry with substantial laboratory research experience in the creation and execution of experimental plans. We particularly seek those with experience of new assay (and ideally product) development for a device or research reagent, especially if that involved translational clinical evaluation. Experience of both evaluating literature methods and of developing new methods using a critical, analytical, skeptical and logical approach to creative problem solving is essential.
With a Team that spans microbiology, molecular biology, biochemistry, biophysics and protein chemistry, we seek candidates with expertise in the in vitro techniques used for the creation, purification, manipulation/labeling, QA and functional characterization of both nucleic acids and recombinant proteins at a molecular level.
ii. Who we are looking for as candidates (behavioural & attitudinal profile)
We seek ambitious candidates who are self-motivated, driven and goal-centric, with the sense of urgency to work efficiently, independently and proactively – ‘self-starters who lead from the front’. We want those that constantly seek to challenge the status quo and raise the bar as part of continuous process and scientific improvement. Tenacity, resilience and the ability to troubleshoot, finding creative solutions in the face of technical and logistical challenges are essential.
Candidates interested in business & commercial translation of IP/discoveries into tangible medical devices & products via a start-up company BAYAN LifeSciences are particularly encouraged to apply.
Those with aspirations to complete higher education via a Masters or PhD at Ateneo de Manila University are similarly welcomed.
We view these roles as excellent career and development opportunities for young researchers wishing to establish & extend themselves. We seek those who want to excel and challenge themselves and their colleagues; those with the leadership potential and aspiration to take on increasingly senior and visible roles and one day become Principal Investigators, leading their own research laboratory in the Philippines to improve the lives of Filipinos.
In BAYAN Life Sciences we envisage a vibrant start-up company with higher paying, better quality jobs that offer enhanced benefits; a company that recruits, rewards & retains the best & brightest; one that pays them fairly for excellent and outstanding performance.
Collectively the IPRDC, AMPLIFIED & IDS programs represent a long-term coherent R&D strategy to help build the Philippines life science research community & the fledgling Filipino diagnostics sector.
Ultimately serving their disadvantaged & underserved fellow Filipinos, we seek those for whom their projects and their careers represent more than just a job — ngunit sa halip ay isang bagay na malapit sa kanilang mga puso.
E) Candidate roles and responsibilities
i) For all Projects
Maintain meticulous, up-to-date laboratory notebooks, reagent inventories, adhering as closely as possible to Good Clinical Laboratory Practice (GCLP).
Via online and face-to-face meetings, communicate frequently yet efficiently with colleagues and collaborators, within & outside of their projects to maximise collaboration, cohesion & communication and to ensure Lean Wastes (especially the Waste of Waiting) are avoided.
Assist with the fitting out of laboratories using ‘Lean Lab’ design principles.
Constantly challenge the status quo, innovate and create process improvements to increase the speed, quality & cost-effectiveness of protein production using Lean Thinking principles.
Explore collaborations to beta-test and then sell the proteins, reagents and diagnostic tests developed as part of the start-up of BAYAN Life Sciences.
Explore & propose grant applications for new & impactful research, including national & international collaborations to accelerate the life science R&D sector.
As appropriate, take on roles of increasing responsibility and independence, ultimately running an independent molecular science R&D laboratory in the Philippines.
ii) For Integrated Protein R&D Centre (IPRDC):
Design and undertake recombinant cloning to create suitable protein expression plasmids. .
Design, execute and interpret experiments to express, purify & characterize recombinant proteins used in molecular diagnostics e.g enzymes for PCR/LAMP and affinity proteins used for ELISA/lateral flow devices.
Ensure the purity, stability & functional activity (quality) of produced proteins are comparable to those of imported proteins using bioanalytical (SDS-PAGE, Western blotting) and functional (enzyme assays, ELISA, affinity determinations) methods.
Work closely with the INTEGRATeD and AMPLIFIED projects to apply IPRDC-generated proteins for development of lower-cost diagnostic devices.
Work closely with chemistry & engineering-based IPRDC projects to integrate their workflows and outputs to maximize the productivity, scalability and cost-effectiveness of the IPRDC.
iii) For Integrated Diagnostic Solutions (IDS) and SARS-CoV2 (AMPLIFIED):
Design, execute and interpret preclinical experiments to develop new methods for the development of (near) point of care tests for Virology (VANQUISHeD), Oncology (CAPTUReD), Cardiometabolic (METABOLISeD) and/or SARS-CoV2 (AMPLIFIED)
Determine the preclinical sensitivity and specificity of prototypes compared with gold standard reference methods.
Characterise the biochemical properties of novel affinity reagents used for the development of affinity-based diagnostics (via ELISA, ELONA, lateral flow).
Optimize biospecimen sample processing for multiple sources (blood, saliva, etc.) to maximise the availability, stability, and functional activity of the target biomarkers.
Collaborate with national & international institutions to expand a clinical biobank used to assess the clinical performance of selected prototype diagnostics.
Perform clinical evaluation of promising prototypes relative to a gold standard diagnostic test to assess clinical sensitivity and specificity
For any prototypes that merit progression, contribute to the writing of a Technical File for submission to the Philippine FDA.
Work closely with colleagues in the IPRDC to functionally compare the performance of BAYAN reagents relative to their imported counterparts. .
As needed, express, purify & characterize recombinant proteins required to reduce the cost of goods for diagnostic tests developed in the INTEGRATeD and AMPLIFIED programs,
Dr. Keith More
Ateneo Research Institute of Science and Engineering
Ateneo de Manila University
Dr. Crisanto Lopez
Department of Biology
School of Science and Engineering
Ateneo de Manila University
Dr. Cybele Abad
Ateneo School of Medicine and Public Health
Ateneo de Manila University
APPLICATION FORM: https://docs.google.com/…/1mJODHV9e2q0UBzQ5j6L1BBl…/edit
Excited for SOSE Week 2022?
The full list of event and activities may be found here: https://bit.ly/SOSEWeek2022_Activities
Congratulations to our Top Faculty Awardees with the highest Scopus- Indexed Publications.
WE ARE PROUD OF YOU!
Panel Discussion on Advancing Optics and Photonics in the Philippines
Panel Discussion on Advancing Optics and Photonics in the Philippines. This event is scheduled for this Saturday, Oct. 30, 2021, at 10 am. This event is the 1st-panel discussion of the 5-week Series (every Saturday) from Oct. 30, 2021, to Nov. 27, 2021, covering technical seminar talks and Panel Discussions.
Looking forward to seeing all of you this Saturday
Zoom Link: bit.ly/ROSESWeeklySeries
Local production of diagnostics to meet health needs in Asia
How much is a COVID-19 RT-PCR test? How easy–or difficult–is it to get tested if you think you may have COVID-19? What about for other diseases? Do you think it would make a difference if these types of tests were manufactured in Asia, or even in your own country?
Join Doctors Without Borders for a special discussion on diagnostics tools–such as tests for different diseases–on November 3, Wednesday. In this webinar, moderated by veteran Filipino journalist and COVID-19 survivor Howie Severino, you can learn about the importance of diagnostics tools in healthcare. Listen as researchers, advocates and innovators discuss the opportunities and challenges of local production in order to meet local needs, especially in Asia. | REGISTER: https://bit.ly/3DYoaT5
Topic: Reclone Symposium: Diagnostics, innovation and local production in Asia-Pacific
Description: Symposium on Diagnostics, innovation and local production in Asia-Pacific to learn about the work of other researchers in the region.
If you have any questions in the meantime, please go to the forum (https://forum.reclone.org/) or contact us via the channels listed on the website (https://reclone.org).
Time: Nov 24, 2021 08:00 AM in London
AGENT-BASED MODELLING OF COVID-19 INFECTION RATE vis-á–vis THE PHILIPPINE GOVERNMENT COMMUNITY QUARANTINE AND FACE COVERING MEASURES
IEEE MIBEC 2021 Virtual Conference
Speaker: Alfonso D. Agustin
TIME: November 27,2021, 13:30 Kuala Lumpur, Malaysia